氯乙酸(MCAA)作為活性化合物,是一種重要的有機精細化工原料,廣泛應(yīng)用于農(nóng)藥(除莠劑)、醫(yī)藥、染料、油田化學(xué)品(鉆井液)、造紙化學(xué)品、塑料助劑(塑料穩(wěn)定劑)、紡織助劑、表面活性劑、電鍍、香料香精等領(lǐng)域。其大用途是生產(chǎn)羧甲基纖維素(CMC),其次是生產(chǎn)巰基乙酸。
隨著技術(shù)進步和發(fā)展,氯乙酸新的應(yīng)用領(lǐng)域逐漸得到開發(fā),前景十分廣闊。據(jù)統(tǒng)計,2005年氯乙酸主要用途為:羧甲基纖維索(CMC)占33%,除草劑2,4-二氯苯氧基乙酸(2,4-D)和樂果占21%,其他用途中,巰基乙酸占14%,兩性表面活性劑占12%,氰基酯和丙二酸鹽占11%。在歐洲,用于 CMC占40%以上,美國用于表面活性劑占20%以上。
氯乙酸的測定有以下幾種方法：1.化學(xué)滴定法；2.酯化氣相色譜法。以上方法操作復(fù)雜，不環(huán)保，酯化法又存在轉(zhuǎn)化率的問題。
滕州市浩瀚色譜儀器技術(shù)服務(wù)有限公司，，研發(fā)出液相色譜法測定氯乙酸及雜質(zhì)二氯乙酸，乙酸等雜質(zhì)的含量，二氯乙酸出峰在氯乙酸之前，無覆蓋，分離好，結(jié)果準(zhǔn)確。
液相柱測定氯乙酸 圖片：



Determination of chloroacetic acid by liquid column
Determination of chloroacetic acid by liquid column

Stationary phase: dedicated
Specification: HH-LYS2019


As an active compound, chloroacetic acid (MCAA) is an important organic fine chemical raw material widely used in pesticides (eliminating agents), medicines, dyes, oilfield chemicals (drilling fluids), paper chemicals, plastic additives (plastics). Stabilizers), textile auxiliaries, surfactants, electroplating, perfume flavors and other fields. Its greatest use is in the production of carboxymethyl cellulose (CMC), followed by the production of thioglycolic acid.
With the advancement and development of technology, new applications of chloroacetic acid have been gradually developed and the prospects are very broad. According to statistics, the main uses of chloroacetic acid in 2005 were: carboxymethyl cellulose (CMC) accounted for 33%, herbicide 2,4-dichlorophenoxyacetic acid (2,4-D) and dimethoate accounted for 21%. In the application, thioglycolic acid accounted for 14%, amphoteric surfactant accounted for 12%, and cyano ester and malonate accounted for 11%. In Europe, CMC accounts for more than 40%, and in the United States, surfactants account for more than 20%.
There are several methods for the determination of chloroacetic acid: 1. Chemical titration; 2. Esterification gas chromatography. The above method is complicated in operation, not environmentally friendly, and the esterification method has a problem of conversion rate.
Tengzhou Haohao Chromatography Instrument Technology Service Co., Ltd., with the advancement of the times, developed high performance liquid chromatography for the determination of chloroacetic acid and impurities such as dichloroacetic acid, acetic acid and other impurities, the peak of dichloroacetic acid before chloroacetic acid, no coverage, Separated and the results are accurate. This column is a vast chromatographic, exclusive development, and is currently applying for patent protection.

Determination of chloroacetic acid by liquid column